Once we have added in the necessary testosterone, the next step is controlling the impending estrogen and progesterone activity that will result from the use of the Nandrolone hormone. This makes the use of anti- estrogens highly recommended; most will need an Aromatase Inhibitor (AI). However, if we suppress estrogenic activity too much, this can lead to complications; it can lead to sexually related side effects as well as damage cholesterol. Conversely, if we do not control estrogen and let the hormone run wild, high levels of estrogen can lead to gynecomastia , water retention and also negatively affect sexual function. Find the right balance of testosterone to estrogen and you will not have a problem when stacking Deca Durabolin.
Although I am usually not inclined to posit speculations on why a particular drug does or doesn't do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body's natural hormonal system, on par with most other oral steroids , but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are