Oxymetholone 50mg opis

Meditech P’s Anadrol-50 is one of the strongest form of anabolic and androgenic steroid, in oral form, ever seen. We often see bodybuilders, athletes, powerlifts and weightlifter gaining 10 to 12 kilograms of body weight in the first couple of weeks of their cycle. However, this is not just muscle weight, but also water retention and fat storage. Why does this happen? Oxymetholone is Dihydrotestosterone (DHT). Normally DHT does not covert into estrogen but unlike other steroids, Oxymetholone does convert into estrogen. Take note that Steroids that convert into estrogen like Oxymetholone tend to come with a lot of side effects.

It is interesting to note that oxymetholone does exhibit some tendency to convert to dihydrotestosterone in the body, although this does not occur via the 5-alpha reductase enzyme. Oxymetholone is already a dihydrotestosterone-based steroid, so no such alteration can take place. Aside from the added c-17 alpha alkylation (discussed below), oxymetholone differs from DHT only by the addition of a 2-hydroxymethylene group. This grouping can be removed metabolically, reducing oxymetholone to the potent androgen 17alpha-methyl dihydrotestosterone (mestanolone). 387 There is little doubt that this biotransformation contributes at least on some level to the androgenic nature of this steroid. Note that since 5-alpha reductase is not involved, the relative androgenicity of oxymetholone is not affected by the concurrent use of finasteride or dutasteride.

There is limited information available on the pharmacokinetics of oxymetholone. [4] It appears to be well-absorbed with oral administration . [4] Oxymetholone has very low affinity for human serum sex hormone-binding globulin (SHBG), less than 5% of that of testosterone and less than 1% of that of DHT. [1] The drug is metabolized in the liver by oxidation at the C2 position, reduction at the C3 position, hydroxylation at the C17 position, and conjugation . [4] [2] The C2 hydroxymethylene group of oxymetholone can be cleaved to form mestanolone (17α-methyl-DHT), which may contribute to the effects of oxymetholone. [3] The elimination half-life of oxymetholone is unknown. [2] Oxymetholone and its metabolites are eliminated in the urine . [1] [2]

Oxymetholone 50mg opis

oxymetholone 50mg opis

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